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KMID : 1094020170340010018
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Journal of Veterinary Clinics
2017 Volume.34 No. 1 p.18 ~ p.22
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Efficacy of Half Dose House Dust Mites-Specific Immunotherapy on Canine Atopic Dermatitis
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Park Jeong-Ho
Lee Wang-Hui
Park Seong-Jun
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Abstract
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The aim of this study was to prove that the hypothesis of half dose (HD) allergen-specific immunotherapy (ASIT) in the treatment of canine atopic dermatitis (CAD) would result in a similar success rate compared to the standard dose (SD) ASIT. Clinical signs were evaluated using a third version of the Canine Atopic Dermatitis Extent and Severity Index (CADESI-03) prior to ASIT (day 0), at the end of induction (day 43), and at three month afterwards (day 90). Of the 18 atopic dogs, 12 dogs (SD group: 6; HD group: 6) had a good - excellent response to the house dust mites-specific immunotherapy. The efficacies of ASIT were 66.6% in both groups. The grades of reduction rate CADESI-03 were not different between two groups. Therefore, half dose protocol of house dust mites-specific immunotherapy is an effective and efficient method to treat CAD.
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KEYWORD
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dog , atopic dermatitis , house dust mite , half-dose , immunotherapy
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